19 Best Nootropics for a better cognitive performance review 2019


Trying to keep up with our modern busy lifestyle has never been harder than it is right now. We live in a competitive world where we have to keep updated, posted and most importantly aware of what’s going on around us. It doesn’t matter what kind of job you have, if you are not there to justify your presence and existence, you are out of the picture.

The idea of being out of the picture brings along with it depression, anxiety, fear of rejection, laziness, weak cognition and low self-esteem and confidence. While these projections can be shown at any moment of human weakness, avoiding them is possible by taking care of your own mental and physical health.

In this article, our main highlight is on how to protect our mental health. For this reason, we are going to discuss the Nootropics, also known as Smart Drugs.

 So what are exactly Nootropics and how do they work?

 In simple words, Nootropics are natural clinical drugs which help to boost brain performance and the cognitive level of a human being. While some of them are approved as a prescription drug in certain countries, others are not authorized by the FDA. They are more likely to be presented in the form of dietary supplement. As a result, we found three types when it comes to Nootropics:

  1. Dietary supplement;
  2. Herbs
  3. Prescription drugs:

How do they work?

 By providing stimulating effects to the brain cells, the Nootropics help in the creation of energy cells through which this later support in enhancing the productivity of the brain. Another thing, Nootropics or smart drugs help in maintaining a free blood flow allowing for more oxygen to reach the brain. This helps in maintaining a good mood, enhancing the memory and staying alert and attentive. Another two great benefits of using these brain supplements are reducing the level of stress/anxiety and increasing the level of dopamine. Both results in good mood switch. This can happen by countering and fighting free radicals that are hosted in the brain by antioxidants.

Therefore, depending on what type of Nootropics you are using, the effects vary tremendously. Not all Nootropics operate equality and offer the same results; each has its own mechanism and functioning system. For this reason, knowing what kind of result you are seeking, you have to choose carefully the Nootropic that goes hand in hand with it.

With the variety of nootropics that are accessible and available in the market, we have collected the best nootropics out there. Throughout this review, you can gain some further information about each of these brain enhancers and understand the difference between them. Hopefully, this review will help you in choosing the right Nootropic that best suits your needs and preferences.

Check out the best smart drugs available on the market:

  1. Dietary Supplements:

Clinical research and meta-analysis have demonstrated that Nootropics have a stimulating effect at the level of the central nervous system which results in improved cognitive performance for both healthy and unhealthy individuals.

  • Omega-3 fatty acids:

This dietary supplement is well known and a lot of people take it on a daily basis. In fact, the Omega 3 fatty acids are 3 types: DHA, EPA, and ALA. The two first DHA and EPA components are recognized for being the most efficacious when it comes to fighting against anxiety and depression. Surprisingly many consumers of omega 3 fatty acids find themselves less likely to be under stress and anxious once they keep up with their daily intakes. However, when it comes to brain cognition or memory boosting or learning development, studies show that there are no proven results that indicate the truth on the effectiveness of this supplement. While it may not have benefits on our mental health, it may be a good supplement for other health problems.

  • Folate:

At a neurological level, the Folate is commonly related to clinical depression, which is a mental disorder that comes with certain characteristics that accompany the patient. These characteristics usually include low self-esteem, bad or sad mood, low energy level, lost in appetite, and so on. According to certain research studies, it is shown that the consumption of Folate acid can have a positive impact on the mental health of the person. This impact resonates in boosting the level of energy as well as diminishing the Homocysteine levels. The homocysteine is usually linked with cognitive outcomes. However, it is still important to consult your doctor before you consume Folate.

  • Vit B6:

An essential supplement and nutrient that comes under the Vitamin B family is the Vit B6 (a.k.a Pyridoxine). Vitamin b6 can be largely found in our daily intake of food and drinks. Depending on the form of the vitamin that exists in the food (both free and bond form), the level of intake varies completely. In fact, pyridoxine is the main element in boosting concentration and cognitive functions in our body. Not only that but it is also effective in boosting alertness and attentiveness levels. It helps in the synthesis of neurotransmitters. By increasing the level of dopamine, this vitamin plays a great role in fighting against depression, anxiety, and exhaustion.

  • Vit B12

This smart drug is commonly referred to as Cobalamin. This vitamin plays a major role in the synthesis of Myelin at the level of the nervous system. It can be largely found in animal products. It can be very hard to find it in sources that are primarily based on vegetables. Therefore, for those who are on a vegan diet, they can consume this supplement in the form of pills. Vit B is water soluble. Research studies indicate that low blood levels of vitamin b12 can lead to certain mental and health diseases including depression, anxiety, and Alzheimer’s. Therefore, a regulated intake of this vitamin can improve these conditions as well as the neurological functioning at large. It will also help diminish and reduce the level of homocysteines that we have previously mentioned.

  • Vit E:

For an effective optimization of brain memory and productivity, this vitamin must be included in the dietary supplement list. Indeed, this Vitamin plays a major role in the brain and mental health in general.  Let me briefly explain this. Since our brain is the most energetic part of our body, free radicals become the common guest of this organ. And if they are not perfectly countered by an antioxidant, it can harm the neurons. This eventually, leads to OXIDATIVE STRESS. This later is something you might want to prevent at any cost because it leads to diseases like Alchemize and others. Therefore, including the vitamin E in your daily diet can have positive benefits on your cognitive performance.


Knowing for its ability of fighting again anxiety and weak concentration, this Nootropic can be largely found in Tea, more specifically in green tea. It can also be detected in fungal species. It is an amino acid. If you are not sure how this supplement works exactly; the explanation is indeed easy. The L-theanine goes beyond the Blood-brain barrier which is basically the defined border that divides the brain from the blood flow. Once it crosses this border, It is capable of increasing the level of dopamine as well as serotonin. Thanks to the presence of psychoactive properties that can be found in this supplement, the L theanine plays a major role in diminishing the mental stress on one hand and boosting cognitive performance on the other hand.

  1. Herbs:

These remain as the most natural and effective brain boosters that ancient people used for a long time. These traditional herbs are considered the safest way to help improve one’s cognitive performance

  • Bacopa monnieri:

Commonly used in Ayurveda, which is an alternative system of medicine, Bacopa monnieri is an herb that does not have an aroma. It is quite known for its potentiality in boosting memory and focus level. In fact, this herb is used by the ancients to memorize long texts. Since then, it gained popularity both locally and internationally for its conventional medical benefits on the human brain. How? Bacopa monnieri has a natural antioxidant impact that improves cognitive performance. Not only that but it also helps in reducing the stress thanks to the adaptogen substances. If you use this natural nootropic helps, there is no need to use antidepressants.

  • Panax ginseng:

After a long day of work, nothing feels better than having a warm cup of ginseng drink. It is by fact, that ginseng is the most well known natural herbal medicine when it comes to mental and physical health issues. Panax ginseng is commonly used in Asian countries for centuries thanks to its positive benefits on human health. It helps in increasing concentrations, boosting the brain productivity and most importantly reducing stress and anxiety. By diminishing the level of cytokines, Panax ginseng functions as both anti-inflammatory and antioxidant. Till today, ginseng can be purchased from many places around the world. However, it can be extremely expensive sometimes and should be consumed in moderate dosages.

  • Ginkgo biloba:

Also known as Maidenhair. Going back almost 270 million years ago, Ginkgo Biloba which is natively from China is considered one of the most ancient trees in history. And despite this long historical existence, the ginkgo tree is yet widely cultivated by the human race. Apart from largely being used as an alternative natural and traditional medicine, it is also a source of food for some. This herb was first associated with Alzheimer research studies. Later on, it was developed to include the hypothesis of being a brain enhancer. Like other ancient herbs that were previously mentioned, the Ginkgo works on increasing the level of dopamine in the brain. As a result, it has a great benefit in reducing stress, anxiety, and fatigue.

  • Salvia officinalis:

Commonly referred to as Sage. This purplish flower largely belongs to the Mediterranean area but it has been placed all over the world. These flowers were primarily used for culinary purposes as well as medical ones. A lot of research studies show that these flowers have positive benefits on the human brain. However, no scientific proof has been presented to judge this statement. The given research shows that the salvia herb is composed of a wide array of active components that play a major role in enhancing and boosting cognitive performance. Besides that, it also fights against neurodegenerative illnesses.

  1. Prescription (Drugs):

Usually authorized by the government and can be medically prescribed for anyone that needs it.

  1. CNS Stimulants:
  • Amphetamine:

Ever since it was discovered, the Amphetamine has been primarily used to treat a patient who has difficulty to maintain focus and attention also for those who behave in a certain way without acknowledging the potential consequences their activities might cause.  These traits are also known to be what ADHD, attention deficit hyperactivity disorder is.

For this reason, these patients were treated by medium to low doses of amphetamine level. Healthy people can also use this stimulant. The amphetamine helps in improving the cognitive performance of the individual by boosting their working memory, improving their concentration and attentiveness and so on. Furthermore, consuming this Nootropic will motivate the person to do activities that require lots of effort and attention. Be aware, that consuming a high level of this stimulant can lead to some unwanted side effects.

  • Methylphenidate:

Commonly used for narcolepsy which is a neurological disorder associated with one’s sleeping cycle. In simple words, it is a sleeping disorder where the person cannot regulate its sleeping time anymore. This disorder is known for excessive sleeping during the daytime. Another disorder that is linked with the Methylphenidate stimulant is the ADHD that we have previously mentioned. It can be both consumed by applying it directly to the skin or by mouth. This stimulant can help to ameliorate catecholamines activities inside the brain. It also helps in improving performance that requires lots of attention and efforts. However, something to keep in mind is that an overdose of this stimulant can lead to adverse effects.

  • Eugeroics:

Eugeroics is another medical drug proven to be effective in the treatment of patients with a sleeping disorder. When we talk about Eugeroics we talk about a stimulating agent that has a primary purpose to keep the person in a state of wakefulness. That means being conscious of the exterior world and what’s happening around that person. This can be tested in terms of the individual behaviors activities and at the level of cognitive performance. The stimulant is also effective in keeping a high level of alertness, meaning that the individual is capable of quickly responding to things to challenges and dangers around him.

  • Caffeine:

Caffeine is the most popular psychoactive stimulant in the whole world. This Nootropic drug is widely consumed by a large population on a daily basis. The very well-known benefit that caffeine can provide to the human brain is alertness and improved memory. One drink that usually has a big amount of caffeine in it is coffee. Of course, coffee is not the only beverage where caffeine can be found. We can actually detect caffeine in tea, energy beverages like Red Bull, in sodas and many more. Once consumed, Caffeine stimulant prevents mental fatigue and decreased attention. By stimulating dopamine, caffeine can help in changing one’s mood for the better. However, it should be noted that excessive consumption of caffeine can have negative effects on the human body. Therefore, it should be taken moderately.

  • Nicotine:

Commonly found in Tobacco, nicotine has always been known as a nootropic psychoactive drug. In recent years, research studies have revealed the functioning of the nicotine system. By synchronizing the nicotinic acetylcholine receptor (nAChR), the nicotine is capable of properly functioning. However, the receptors themselves will become less sensitive and unresponsive, if there is a high nicotine dosage. Therefore, nicotine should be consumed in low doses for effective results. They are the answer to brain weakness. We found lots of people who smoke being too alert and attentive to things. This is primarily due to nicotine. Still, smoking is not something one should avert to in order to increase attentiveness, alertness, and cognition. Tobacco consumption should not be encouraged as it has negative effects on the human body.

  1. Cognitive enhancers: Racetams, such as
  • Piracetam:

 Piracetam, known as the first nootropic ever prospered in 1964, It was first introduced by the Romanian doctor, Corneliu E. Giurgea. The piracetam falls under the racetams family class. It was first used as a calming medicine. While research studies show that this synthetic molecule can have positive benefits on the cognition performance, proves are still yet to be confirmed. Some of the reviews indicate that piracetam might reduce anxiety and depression level. However, there is no clear evidence of its overall effects at the level of memory improvement. It is not approved in certain countries therefore if you are going to purchase this cognitive enhancer, you must first check its availability and legal status in your country.

  • Oxiracetam:

Another nootropic that falls under the racetam group is oxiracetam. Thanks to its developed format, this nootropic requires less duration to provide the same nootropics benefits as Piracetam. Knowing for its capability in enhancing memory and boosting one’s learning abilities; the oxiracetam is indeed an effective brain enhancer. You are probably wondering how it actually works? By providing a stimulating effect at the level of AMPA receptors in the brain, the oxiracetam can enhance cognition performance. Also, an increased presence of acetylcholine (ACh) leads to strengthening your memory, your concentration, and focus levels. The good thing about this Nootropic is its overconsumption would not lead to serious side effects. In fact, research shows that it is safe to consume it for a long period of time.

  • Phenylpiracetam:

Say goodbye to your anxiety with this nootropic stimulant. The phenylpiracetam also is known as Phenotropil was first developed in 1983 in Russia. This smart drug is commonly used by athletes to boost their physical and mental strength.

It is recognized to be more potent than the two previously racetams mentioned above. Thanks to its stimulatory effects, this nootropic can help you recover your memory and boost our cognition. How? The Phenotropil allows for a free flow of blood this prevents the blood vessels from compressing and consequently more oxygen is able to reach the brain cells, this procedure helps in improving cognition and boosting one’s mood.

  • Aniracetam:

While it might be approved in Europe, this synthetic drug is not authorized in America as a prescription drug according to the food and drug administration FDA. The aniracetam was first developed and synthesized in the late 1970s by a multinational healthcare company originated in Swiss known as Hoffmann-La Roche. While some of the other racetams could be only consumed once they are dissolved in water, this Nootropic is fat-soluble. That means it should be consumed with some kind of fat (spoonful of natural virgin oil). Endorsing certain neuroprotective qualities, the aniracetam is capable of enhancing your memory and focus as well as to look out for brain damage and repair it. How? By diminishing the glutamate receptors’ level of sensations, more neurotransmitters will be present inside the brain. This results in an improved cognition performance.


In this review, we have tried to point out the necessary key information for each Nootropic available on the market. The best way to know which one will offer you an effective result is by trying them yourself and see how our brain and body react to them. As you can tell, each Nootropic is different from the other. Most of them are recommended to be consumed on a moderate to low doses to avoid any negative side effects. The most recommended ones are herbs Nootropics since there are no particular side effects and they are safe to use on a daily basis. Supplements are the thing right now. A lot of people use it and there are lots of good reviews when it comes to dietary supplements.